Pharmacology and Toxicology Quizzes
1- Phospholipase C generates PIP2 generates DAG hydrolyzes IP3 all of the above
2- PLCgamma is activated by platelet-derived growth factor tyrosine phosphorylation Gq - protein the first two are correct
3- Enzyme that cleaves at the red line PLA2 PLC PLD PLA2 and diacylglycerol lipase
4- IP3 is catabolized by inositol phosphatase phosophodiesterase none the above
5- Not an IP3 receptor domain N-terminus IP3 binding site ATP-binding catalytic domain regulatory domain with phosphorylation sites six transmembrane domain
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Answers:
1- Phospholipase C Answer: generates DAG
2- PLCgamma is activated by Answer: the first two are correct (platelet-derived growth factor AND tyrosine phosphorylation)
3- Enzyme that cleaves at the red line Answer: PLA2 and diacylglycerol lipase
4- IP3 is catabolized by Answer: phosphatase
5- Not an IP3 receptor domain Answer: ATP-binding catalytic domain