Pharmacology and Toxicology Quizzes  

Diacylglycerol and Protein Kinase C Quiz 1

1- DAG activates
PLC
PKC
DAG kinase
all of the above


2- Phorbol esters do not activate
classic PKCs
novel PKCs
mue PKCs
atypical PKCs


3- Acts as a pseudosubstrrate
DAG
calcium
PKC regulatory domain
PKC inhibitory peptide chain


4- Not a PLD isozyme
sodium-oleate dependent PLD
phosphatidic PLD
ADP-dependent PLD
ribosylation factor


5- DAG may induce the release of more DAG by the following patway
G-protein
PKC PLC DAG PLD
G-protein
PLD DAG PKC PLC
G-protein
PLC DAG PKC PLD
none of the above


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Answers:

1- DAG activates
Answer: PKC


2- Phorbol esters do not activate
Answer: atypical PKCs


3- Acts as a pseudosubstrrate
Answer: PKC regulatory domain


4- Not a PLD isozyme
Answer: phosphatidic PLD


5- DAG may induce the release of more DAG by the following patway
Answer:
G-protein PLC DAG PKC PLD