Pharmacology and Toxicology Quizzes  

Diacylglycerol and Protein Kinase C Quiz 2

1- DAG is metabolized by
phosphorylase
DAG kinase
DAG lipase
the first two are correct


2- Calcium activates
classic PKCs
novel PKCs
mue PKCs
atypical PKCs


3- Not a regulator of PKCs
cell-permeable DAG analogs
inhibitor drugs
mue analogs
pseudosubstrate inhibitors


4- Phosphatidic acid may be metabolized to DAG by:
phosphatidic acid kinase
phosphatidic acid phosphorylase
PLD
none of the above


5- DAG relieves inhibition of
catalytic site of PKC

pseudosubstrate site of PKC

pseudosubstrate site of PLD

the first two are correct


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Answers:

1- DAG is metabolized by
Answer: DAG kinase


2- Calcium activates
Answer: classic PKCs


3- Not a regulator of PKCs
Answer: mue analogs


4- Phosphatidic acid may be metabolized to DAG by:
Answer: phosphatidic acid phosphorylase


5- DAG relieves inhibition of
Answer: catalytic site of PKC