Pharmacology and Toxicology Quizzes
1- PLA2 are directly activated by PKC PKC and Ca2+ PKG PKG and Ca2+
2- EDGs are G-protein receptors second messengers activated by DAG all of the above
3- Arachidonic acid is metabolized by cytochrome P450 into prostaglandins thromboxanes leukotrienes EETS
4- Makes HPETES from arachidonic acid cyclooxygenases lipoxygenases P450 the first two are correct
5- Lipoxygenases require Ca2+ ATP hydroperoxy acid all of the above
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Answers:
1- PLA2 are directly activated by Answer: PKC and Ca2+
2- EDGs are Answer: G-protein receptors
3- Arachidonic acid is metabolized by cytochrome P450 into Answer: EETS
4- Makes HPETES from arachidonic acid Answer: lipoxygenases
5- Lipoxygenases require Answer: all of the above (Ca2+ AND ATP AND hydroperoxy acid)