Pharmacology and Toxicology Quizzes  

Kinases and Phosphatases Quiz 2

1- Kinases
form Tyr phosphomonoesters
use ATP as a donor
may use Mg2+ as a cofactor
all of the above


2- About __ of expressed proteins are phosphoproteins
1/8
1/4
1/3
1/2


3- Will inactivate a Ser/Thr/Tyr kinase
mutation at Lys72
Ser changed to Asp
Thr changed to Asp
all of the above


4- Ser/Thr phosphatase metalloenzyme
PPP
PPM
tyrosine phosphatases
the first two are correct


5- A PPP phosphatase
PP4

PP2A

PP5

all of the above


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Answers:

1- Kinases
Answer: all of the above (form Tyr phosphomonoesters AND use ATP as a donor AND may use Mg2+ as a cofactor)


2- About __ of expressed proteins are phosphoproteins
Answer: 1/3


3- Will inactivate a Ser/Thr/Tyr kinase
Answer: mutation at Lys72


4- Ser/Thr phosphatase metalloenzyme
Answer: the first two are correct (PPP AND PPM)


5- A PPP phosphatase
Answer:
all of the above