Pharmacology and Toxicology Quizzes  

Kinases and Phosphatases Quiz 3

1- Phosphorylation occurs
to activate a protein
to deactivate a protein
at multiple sites in the protein
all of the above


2- Phosphatases and kinases make up __% and __% of the known genome, respectively
0.2-0.3% and 0.8-1.0%
0.3-0.8% and 1.0-2.0%
0.8-1.0% and 0.2-0.3%
1.0-2.0% and 3.0-8.0%


3- Creates a constitutively active Ser/Thr/Tyr kinase
mutation at Lys72
Ser changed to Asp
Lys changed to Asp
all of the above


4- Mechanism involves a single step
PTP
PPM
dual specificity phosphatase
all of the above


5- A PPM phosphatase
PP1

PP2

PP2A
PP2B


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Answers:

1- Phosphorylation occurs
Answer: all of the above ( to activate OR deactivate a protein AND at multiple sites in the protein)


2- Phosphatases and kinases make up __% and __% of the known genome, respectively
Answer: 0.8-1.0% and 0.2-0.3%


3- Creates a constitutively active Ser/Thr/Tyr kinase
Answer: Ser changed to Asp


4- Mechanism involves a single step
Answer: PPM


5- A PPM phosphatase
Answer:
PP2