Pharmacology and Toxicology Quizzes  

Kinases and Phosphatases Quiz 4

1- Not true
all phosphates may be dephosphorylated
cells maintain a steady-state ratio of phosphorylated to dephosphorylated protein
phosphorylation alters interactions with other molecules
some kinases are controlled by phosphorylation


2- Not a kinase gene family
Ser/Thr/Tyr kinases
mitochondrial Ser/Thr kinases
dual-specificity kinases
DNA-protein kinases


3- Also known as calcineurim
PP1
PP2
PP2A
PP2B


4- Mechanism involves two steps
PTP
pyruvate dehydrogenase phosphatase
PP2
PP4


5- Tyrosine phosphatase
may be Tyr specific or dual specificity

have a high molecular weight

form a tyrosiny intermediate
the first two are correct


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Answers:

1- Not true
Answer: all phosphates may be dephosphorylated


2- Not a kinase gene family
Answer: dual-specificity kinases


3- Also known as calcineurim
Answer: PP2B


4- Mechanism involves two steps
Answer: PTP


5- Tyrosine phosphatase
Answer: may be Tyr specific or dual specificity