Career Leaders for Innings Pitched
Minimum of 3.1 PA/G, 1.0 IP/G, and 0.1 decision/G for career leaderboards for rate statistics.
| Rank | Player | Innings |
| 1. | Tim Hudson | 1320 |
| 2. | Roy Oswalt | 1125 |
| 3. | Javier Vazquez | 1099 |
| 4. | Roy Halladay | 1096 |
| 5. | Barry Zito | 1053 |
