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Malaria prophylaxis

The ABC of Malaria

Be Aware of the malaria risk. No prophylaxis is totally effective. Malaria must be considered in anyone with a fever who has visited an endemic area within the last year.

Avoid being Bitten

Take appropriate Chemoprophylaxis for one week before travel (2 1/2 weeks in the case of mefloquine), while abroad, and for four weeks after travel.

Appropriate chemoprophylaxis is given below. Note: even if every precaution is taken, malaria is still a possibility. No protection can be 100% effective.

Therefore any fever or 'flu-like illness within a year of overseas travel (and especially within the first three months) could be malaria and needs IMMEDIATE medical attention.

Destination

Recommended

regimen

Alternative

regimen

Destination

Recommended

regimen

Alternative

regimen

Abu Dhabi

W

 

Libya

W

 

Afghanistan

PC

«

Madagascar

ME or DO or MON

PC

Algeria

W

 

Malawi

ME or DO or MON

PC

Angola

ME or DO or MON

 

Malaysia Sabah

Deep forests of peninsular Malaysia

Sarawak and elsewhere in Malaysia

ME or DO or MON

PC

W

PC

Argentina small area NW only

C

P

Mali

ME or DO or MON

PC

Armenia

C

«

Mauritania

PC

DRF

Azerbaijan south border

C

P

Mauritius rural areas

Elsewhere

C

W

P

Bali

W

 

Mayotte

ME or DO or MON

PC

Bangladesh

East and Chittagong Hill Tracts

Elsewhere (no risk in Dhaka City)

ME or DO or MON

PC

«

«

Mexico Main tourist areas

Rural areas rarely visited by tourists

W

C

P

Belize rural

C

P

Morocco

W

 

Benin Republic

ME or DO or MON

PC

Mozambique

ME or DO or MON

PC

Bhutan

PC

«

Myanmar (Burma)

ME or DO or MON

PC

Bolivia Amazon Basin

Other rural below 1500m

ME or DO or MON

PC

PC

DRF

Namibia

PC

MPM

Botswana northern half November-June

PC

DRF

Nepal below 1300m (no risk in Kathmandu)

PC

«

Brazil

Amazon basin, Mato Grosso & Maranhao

Elsewhere in Brazil

ME or DO or MON

W

PC

Nicaragua

C

P

Burkina Faso

ME or DO or MON

PC

Niger

ME or DO or MON

PC

Burundi

ME or DO or MON

PC

Nigeria

ME or DO or MON

PC

Cambodia Phnom Penh

Western Provinces

Elsewhere

W

DO

ME or DO or MON

«

«

Oman (Rural areas only)

PC

«

Cameroon

ME or DO or MON

PC

Pakistan below 2000m

PC

«

Cape Verde Islands

W

 

Panama East of Canal

West of Canal

PC

C

DRF

P

Central African Republic

ME or DO or MON

PC

Papua New Guinea

DO

ME

Chad

ME or DO or MON

PC

Paraguay rural only October - May

C

P

China Main tourist areas

Yunnan and Hainan

Remote rural areas

W

ME or DO or MON

C

PC

P

Peru below 1500m

PC

DRF

Colombia below 800m

ME or DO or MON

PC

Philippines rural areas below 600m

Cebu, Leyte, Bohol, Catanduanes

PC

W

DRF

Comoros

ME or DO or MON

PC

Rwanda

ME or DO or MON

PC

Congo

ME or DO or MON

PC

Sabah

ME or DO or MON

PC

Congo Dem. Rep

ME or DO or MON

PC

Sao Tome & Principe

ME or DO or MON

PC

Costa Rica rural below 700m

C

P

Saudi Arabia

(no risk N, E, central provinces, Asir)

Western border cities

Elsewhere

W

W

PC

 

 

«

Djibouti

ME or DO or MON

PC

Senegal

ME or DO or MON

PC

Dominican Republic

C

P

Sierra Leone

ME or DO or MON

PC

Ecuador below 1500m

PC

DRF

Solomon Islands

DO

MPM

Egypt El Faiyum June - October

Elsewhere in Egypt

C

W

P

Somalia

ME or DO or MON

PC

El Salvador

C

P

South Africa

Lowlands of NE Transvaal and Natal

Elsewhere

ME or DO or MON

W

MPM

Equatorial Guinea

ME or DO or MON

PC

Sri Lanka (no risk in Colombo)

PC

«

Eritrea

ME or DO or MON

PC

Sudan

ME or DO or MON

PC

Ethiopia

ME or DO or MON

PC

Surinam

ME or DO or MON

PC

French Guiana

ME or DO or MON

PC

Swaziland

ME or DO or MON

PC

Gabon

ME or DO or MON

PC

Syria rural north May - October

C

P

The Gambia

ME or DO or MON

PC

Tajikistan

C

P

Ghana

ME or DO or MON

PC

Tanzania

ME or DO or MON

PC

Goa

PC

«

Thailand Bangkok, tourist centres and rural areas away from borders

Staying on Cambodia or Myanmar border

W

DO

 

«

Guatemala below 1500m

C

P

Togo

ME or DO or MON

PC

Guinea Bissau

ME or DO or MON

PC

Turkey

(No risk west of Antalya) Antalya, Side, Alanya and east coast, plain around Adana SE Anatolia, March - November

C

P

Guinea

ME or DO or MON

PC

Turkmenistan (SE only, Mary District)

C

P

Guyana

ME or DO or MON

PC

United Arab Emirates rural north

PC

«

Haiti

C

P

Vanuata

DO

MPM

Honduras

C

P

Venezuela

Amazon basin

Rural (no risk Caracas or Margarita)

ME or DO or MON

PC

PC

DRF

Hong Kong only in borders New Territories

W

 

Vietnam (no risk in cities and Red River delta)

ME or DO or MON

«

India (no risk in mountain states)

PC

«

Yemen

PC

ME

Indonesia Irian Jaya

Bali and Cities

Elsewhere in Indonesia

ME or DO or MON

W

PC

PC

DRF

Zambia

ME or DO or MON

PC

Iran March - November

PC

«

Zimbabwe Zambezi Valley

Elsewhere below 1200m November - June

ME or DO or MON

PC

«

DRF

Irian Jaya

ME or DO or MON

«

 

 

 

Ivory Coast

ME or DO or MON

PC

« = Seek Advice from malaria laboratory for alternative regimens

 

 

Kenya

ME or DO or MON

PC

 

 

 

Laos (minimal risk in Vientiane)

ME or DO or MON

«

 

 

 

Liberia

ME or DO or MON

PC

 

 

 

 

 

 

Key to regimens

MON

Malarone (atovaquone / proguanil), one tablet daily. Begin 2 days before departure, continue while in malarious area and for 7 days after return (still one tablet daily). Not licensed for children, nor for more than 1 month in malarious areas.

PC

Proguanil (Paludrine) 200mg daily (= 2x100mg tablets)

Plus Chloraquine 300mg base weekly (= Avlocler 2x250mg or Nivaquine 2x200mg)

ME

Mefloquine, one 250mg tablet weekly for visits up to one year. Avoid first trimester of pregancy, lactation, or if pregnancy likely within three months of stopping mefloquine. Contraindicated if previous serious psychiatric illness, previous fir or family history of epilepsy in first-degree relatives. Metoclopramide accelerates absorption. Travellers should start mefloquine 2½ weeks before travel (three doses before leaving UK).

C

Chloroquine 200mg base weekly

(= Avlocler 2x250mg or Nivaquine 2x200mg)

P

Proguanil 200mg (= 2x100mg tablets) daily

W

No chemoprophylaxis but be aware of risk. Avoid mosquito bites and carry standby treatment if going to be far from medical facilities

MPM

Maloprim, one tablet weekly (= Avlocler 2x250mg or Nivaquine 2x200mg).

Seek specialist advice for stays over six months

DO

Doxycycline, one table of 100mg daily.

Not for children or pregnant women. Be aware of photosensitivity risk.

Seek specialist advice for stays over three months

DRF

In the alternative regimen column, the letters DRF stand for Drug-Resistant-Falciparum regimen. DRF = MR or DO or MON

«

Seek Advice from malaria laboratory for alternative regimens

Telephone sources of advice

Malaria Reference Laboratory 09065 508 906 (24-hour helpline).

£1 per minute at all times.

Birmingham 0121 424 0357 / 3354 / 2357, Glasgow 0141 300 1130,

Liverpool 0151 708 9393, Oxford 01865 225 214

This chart is based on advice given by the London School of Hygiene and Tropical Medicine, and the Malaria Reference Laboratory, June 2001. It will not be updated, so seek out more up to date advice before you travel. The information presented here should be used as a guide to help planning, and must not be used as professional or expert advice. We cannot accept any responsibility for your use of this chart or consequences of using it - you must see your Doctor for professional advice on Malaria and other preventative measures.

 

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