On Christmas Eve, Jerry (recurring guest star ABRAHAM BENRUBI) becomes suspicious of Lee when he sees her closing Greene's locker and Greene's personal items later turn up missing. No one believes Jerry, but he's right. Lee is obsessed with Greene.

Corday treats David Gardner (TOM AMANDES), an attractive 44-year-old symphony trumpet soloist concerned that the surgery needed to remove his prostate cancer will make him sexually dysfunctional. She adeptly calms his fears. Aware of their mutual attraction, the two share supper at Doc Magoo's.

Paramedics transport an 18-year-old flatlined boy. After Carter successfully resuscitates him, the teen's heart beats, but he's brain dead. Later, a 16-year-old girl with liver failure, who desperately needs a transplant, enters the emergency room. Her type AB blood matches only two percent of the population--but it is the same blood type as the brain-dead boy. Carter gets his Christmas miracle when the boy's mother, Mrs. Richards (LAURIE O'BRIEN), agrees to donate her son's liver to the girl.

Benton cannot have dinner at his sister's house because Romano, as usual, gives his own work to Benton to complete. After Romano leaves, one of his patients, Mr. DeMisa (TRAVIS McKENNA), requires emergency surgery, but Romano doesn't respond to his page. Benton begins surgery, and Romano finally arrives--drunk. When Benton won't let him operate, Romano threatens to terminate Benton's residency. Fortunately, Benton proves Romano's intoxication with a blood test. After a hectic day, Benton cheers up when Carla brings Reese to the hospital to see him.

Hathaway and Ross' different religious beliefs become apparent when Ross and Hathaway disagree on how a pregnant 13-year-old should deal with her situation. However, after refusing to attend Mass with Hathaway's family, Ross reconsiders and goes.