Federal Bureau of Investigation (FBI) agents Lance Carmichael (NATHAN LeGRAND) and Robert Clayton (JOHN ROSENFELD) bring Amber (SANDRA TAYLOR), a stripper, to the hospital with a gunshot wound to her chest. Carmichael and Clayton insist on total secrecy and take all papers containing her test results with them. Greene refuses to transfer Amber to another facility, but the men take her anyway. Later when FBI agent Hoffman (GEORGE McDANIEL) arrives at the hospital searching for Amber, Greene realizes that Carmichael and Clayton were not really affiliated with the FBI.

Carter watches Lucy swallow a pill and confronts her. She admits she uses Ritalin, a medication for attention deficit disorder and hyperactivity in children. She's been taking the prescription ever since she was in the fifth grade. Carter suggests it's time for her to quit. Due to Hathaway's behavior, Weaver concludes that Hathaway is pregnant. Weaver tells her to opt out of treating any patients that might be a risk to the baby. Hathaway calls Ross to tell him she's pregnant and is disappointed when he tells her he won't be returning to Chicago.

Three teenagers involved in a car accident get rushed to the emergency room. Sixteen-year-old Shannon Mitchell (MAGGIE LAWSON - "Pleasantville") experiences paralysis below the waist from a spinal cord injury. The 18-year-old driver, Justin Casey (NATHAN WEST), sustained minor burns from pulling 17-year-old Travis Mitchell (ERIC CHRISTIAN OLSEN) out of the vehicle after the gas tank exploded. Mitchell suffers severe burns with a slim chance of surviving. Casey's blood alcohol tests positive, but he insists the accident occurred as a result of wrestling over what music to play on the compact disc player--not alcohol. Just when Romano thinks he's convinced Benton to join his cardiothoracic team, Benton gets selected for and accepts the trauma fellowship.