Chief of staff Dr. Donald Anspaugh (recurring guest star JOHN AYLWARD) informs a disappointed Weaver that her official title has changed from acting chief of emergency medicine to interim chief. Greene agrees to be on the search committee to consider candidates to fill the interim position permanently. Despite Weaver's objections, Ross gets the job as the new pediatric emergency room attending doctor. He discovers a teenage girl, Dana (recurring guest star ASHLEY JOHNSON), has cancer of the leg and must defend her rights to her parents who want to amputate.

Jeanie Boulet returns from her vacation ready to work. Benton discusses Reese's deafness with Carla (recurring guest star LISA NICOLE CARSON). Corday watches them and mistakenly thinks they're reuniting until Benton reluctantly tells her about Reese.

Greene's daughter, Rachel, pleads with Greene to help a horse in a trailer outside the ambulance bay. He administers an enema. Rachel is proud of her father for helping the horse. Greene's first assignment as an EMS director places him in danger as he treats a dynamite-wired assailant with gunshot wounds. Greene wears a bomb suit and examines the patient. After paramedics rush the bomber to the hospital, Benton works on him, but the patient still has a detonator box entangled in his intestines. When the box starts to hiss, Benton cuts the intestines, removes the box and throws it in a corner. It explodes. No one is hurt.

Carter saves an elderly woman and places her on a ventilator. He later finds out she is a DNR (do not resuscitate) and reluctantly removes her from the ventilator. A confused Lucy observes as Carter stays with his patient, who eventually dies. Roxanne Please returns to have her foot examined by Carter. She flirts with him. Later, at Carter's dorm room, Roxanne competently assembles his expensive stereo system and the young couple share a romantic moment as they slow dance.