Millicent Carter (recurring guest star FRANCES STERNHAGEN - "Cheers") encourages her grandson, Dr. Carter, to seek professional help. Carter, who has been living with her since his traumatic attack, can't sleep. He consults with Dr. DeRaad (JOHN DOMAN), County General's chief psychiatrist. Later, Carter meets with his attacker's wife. Abby treats Delia (DAKOTA FANNING), a 5-year-old car accident victim. Tests prove a recurrence of Delia's leukemia. A previous search for a bone marrow donor netted no results. Her father, Avery Chadsey (STEVEN FLYNN - "Ulee's Gold"), is not a match. Abby discovers that Avery has a child, Jessamyn (JULIE MARIE BERMAN), with his first wife. Against Avery's wishes, Abby meets with Jessamyn and convinces the 16-year-old to test as a donor.

Cleo and Benton visit Jackie's (recurring guest star KHANDI ALEXANDER - HBO's "The Corner") house. Although Jackie likes Cleo, she warns her brother that Cleo appears uninterested in a serious, long-term relationship. Weaver returns to work after her suspension. Carter administers to 76-year-old Ruth Pooler (RUTH MANNING), an asthma patient with high blood pressure. Unable to afford her own prescriptions, she took her husband's medication and became ill.

After his father is treated for pneumonia and released from the hospital, Greene takes Greene Sr. to Lake Michigan. Here, Greene Sr., a former naval officer, goes on his last boat ride.

Kovac helps Hathaway purchase a used car at a dealership. Later, he recounts to her how his wife and children died during the Bosnian war. Unfortunately the car stops working. They sit on the car and share their first kiss.