Greene prepares for his tenure review next week, hoping to join the faculty. His main competition is Weaver. When Weaver tries to recruit subjects for a grant to study the physical behavioral patterns of night-shift workers, Jeanie feels obligated to help Weaver, so she joins the study.

Hathaway and Ross volunteer to perform a designated safety check to help Greene. They make a good team as they round up dangerous equipment. The former lovers stumble upon a room where they used to meet, and they recall old memories.

After stealing expensive silverware from Hathaway's home on Christmas Eve, Charlie comes to the emergency room to get money from Ross to pay her pimp. Not believing her claim that she is in danger, Ross refuses her. Later, Charlie returns to the hospital, beaten and raped.

Benton finds Keaton cuddling with Carter on her couch just before she leaves the emergency room to go work in Pakistan. The mortified Keaton assumes that Benton will blackmail her in order to get another rotation in pediatric surgery. But Benton's ethics will not allow him to do that.

Gant feels Benton is being too tough on him. But when Gant's mistake nearly causes a young patient to die, Benton gets even tougher.

Greene puts his career in jeopardy when he treats a woman who refuses to give her consent. Later, he and nurse Chuni Marquez (recurring guest star LAURA CERSN) subtly flirt during the night shift. After work, they consummate their attraction to each other in Greene's bedroom.

Benton, Carter and Doyle feverishly work to save a victim who either tripped or threw himself in front of a subway. Although the patient is unrecognizable due to the injuries, they soon realize the victim is Gant.