Marlee Matlin (as Amanda), Elaine Hendrix (as Jennifer), Barry Newman (as Frank), Robert Bailey Jr. (as Reggie), John Ross Bowie (as Elliot), Armin Shimerman (as Man in subway), Robert Blanche (as Bob), David Albert (as Himself), Marsha Clark (as Voices (voice)), James Langston Drake (as Groom), Dan Finnerty (as Wedding DJ), Amit Goswami (as Himself), John Hagelin (as Himself), J.Z. Knight (as Ramtha (as Ramtha)), Sherilyn Lawson (as Bridesmaid 2), Michele Mariana (as Tour Guide), Eric Newsome (as Voice over animated characters), Dawnn Pavlonnis (as Bridesmaid), Candace Perth (as Herself), Ramtha (as Herself), Mercedes Rose (as Brides Maid), Jeffrey Satinover (as Himself), Jeff S. Dodge (as Extra (on train)), Carol Stanzione (as (voice)), Leslie Taylor (as Bride's Sister), William Tiller (as Himself), Tin Tran (as Guy #2 (as Tin Tran)), Tara Walker (as Girl at Train Station), Fred Alan Wolf (as Himself)

SINOPSIS:
"WHAT THE #$*! DO WE KNOW?!" is a radical departure from convention. It demands a freedom of view and greatness of thought so far unknown, indeed, not even dreamed of since Copernicus. It's a documentary. It's a story. It's mind-blowing special effects. This film plunges you into a world where quantum uncertainty is demonstrated - where neurological processes, and perceptual shifts are engaged and lived by its protagonist - where everything is alive, and reality is changed by every thought.