Blockbuster Entertainment Awards

- 1998 - Best Actress, Comedy for "My Best Friend's Wedding" (W) 

- 1998 - Best Actress, Thriller for "Conspiracy Theory" (W)

- 1999 - Best Actress, Drama for "Stepmom" (W)  ~pics~

- 2000 - Best Actress, Comedy/Romance for "Notting Hill" and "Runaway Bride (N)
- 2001 - Best Actress, Drama for "Erin Brokovich" (W)

People's Choice Awards

- 1998 - Best Actress (W) ~pics~

- 2000 - Favourite Motion Picture Actress (W)~pics~

- 2001 - Favourite Motion Picture Actress (W)~pics~

BAFTA Awards

- 1998 - Best Performance by an actress in a Motion Picture - Comedy/Musical for "My Best Friend's Wedding" (N) ~pics~
- 2001 - Best Performance by an actress in a Motion Picture - Drama for "Erin Brokovich" (W)

MTV Movie Awards

- 1998 - Best Female Performance for "My Best Friend's Wedding" (N)

- 2000 - Best Female Performance for "Runaway Bride". (N)

Emmy Awards

- 1999 - Best Outstanding actress for a guest role in a Drama series for "Law and Order" (N) ~pics~

The Screen Actors Guild Awards

- 2001 - Outstanding Performance by a Female Actor in a Leading Role for "Erin Brokovich" (W) ~pics~

Moviefone Moviegoer Awards

- 2001 - Outstanding Actress for "Erin Brokovich" (W)

Showest Awards

- 1991 - Female Star of The Year (W) 

- 1997 - International star of the year (W)   ~pics~

Hasty Pudding Theatricals, USA

- 1997 - Female of the year (W)

Critics Associations Awards

- 2000 - Boston Society of Film Critics (Runner-Up)- 2000

- Broadcast Film Critics Association (W)~pics~
- 2000 - Chicago Film Critics Awards (N)
- 2000 - Los Angeles Film Critics Association (W) ~pics~
- 2000 - National Board of Review (W) ~pics~
- 2001- The London Film Critics' Circle (W)