Suffering from uranium poisoning as a young girl, Jessica Drew was at the point of death when her geneticist father injected her with a serum derived from spider venom. After decades in stasis as the serum took hold, Jessica reawoke into the contemporary world with tremendous powers. Initially trained by Hydra, she rebelled against them and joined S.H.I.E.L.D., where she's a valued asset.
Current Version:
Spider-Woman (Classic)
Alternate Versions:
Kuurth, Breaker of Stone