Illinois 146 is a significant east-west route in far southern Illinois, running from near Cape Girardeau to Cave-in-Rock, in the southeast corner of the state.
Intersections from west to east:
IL146 begins on a Mississippi River crossing near Cape Girardeau, MO
IL146 joins IL3 north
IL146 breaks off and heads east at Ware
IL127 joins from the north
IL127 breaks off and heads south at Jonesboro
US51 at Anna
US45 at Vienna
IL34 joins from the north
IL34 leaves south to run to Rosiclare
IL146 ends at IL1 near Cave-in-Rock.
It passes through these towns: East Cape Girardeau, Ware, Jonesboro, Vienna, Golconda, and Elizabethtown.