Objectives
  • Disseminate info on TB in India
  • Improve care of TB patients in India
  • Enable doctors and NGO's interested in TB control to interact
Acceptable regimens in the presence of MDR TB(WHO recommendation)
Situation B:Susceptibility test results are available before starting the new treatment:
Resistance to isoniazid alone or in combination with resistance ot streptomycin(and/or with thiacetazone)
Resistance to isoniazid and ethambutol with or without resistance ot streptomycin
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Resistance to Initial phase Continuation phase
Drugs Minimum
Duration
in months 		Drugs Duration
in months
*Isoniazid
(Streptomycin
thiacetazone 		1.rifampicin
2.aminoglycosidec
3.pyrazinamide
4.ethambutol 		2-3
2-3
2-3
2-3
 1.rifampicin
2.ethambutol 		6
6
*Isoniazid
and ethambutol
(streptomycin) 		1.rifampicin
2.aminoglycoside
3.pyrazinamide
4.ethionamide d 		3
3
3
3
 1.rifampicin
2.ethionamide 		6
6
c)Streptomycin ,if still active;if resistance to streptomycin,use Kannamycin or Capreomycin
d)if ethionamide is not available or poorly tolerated(even at a dose of 500 mg /day)use ofloxacin