The series follows the life of a teenage Clark Kent living in the town of Smallville, Kansas, that is set at the start of the 21st century. It shows Clark Kent coping with adolescence while he is developing superpowers, exploring his extraterrestrial origins, and struggling to find his destiny in life.
The series often deals with the people in Clark Kent's life: the trials and tribulations of his adoptive human parents, Jonathan Kent and Martha Kent; friendship with his peers Chloe Sullivan and Pete Ross; his attempts at a relationship with his sometimes love interest, Lana Lang; and especially his peculiar friendship with a young Lex Luthor.
The element of Kryptonite is used as a recurring plot device throughout the series. Kryptonite is shown to have bizarre and lingering effects on human physiology and the young superhero often encounters mutated villains who have developed bizarre powers, such as psychic abilities, shapeshifting, and other paranormal abilities
Main Characters:
Clark Kent
Lana Lang
Lex Luthor
Pete Ross
Chloe Sullivan
Jonathan Kent
Martha Kent
Lionel Luthor
Lois Lane
Kara Kent
Shelby
Supporting Cast:
Jimmy Olsen
Jason Teague
Major Sam Lane
Lucy Lane
People of Metropolis:
Lt. Maggie Sawyer
Morgan Edge
Perry White
Pauline Kahn
Tess Mercer
Other Superhuman People:
J'onn J'onzz
The Angel of Vengeance
Justice League:
Green Arrow
Black Canary
Aquaman
Cyborg
Impulse
The Legion of Super-Heroes:
Cosmic Boy
Lightning Lad
Saturn Girl
Villains:
Brainiac
Bizarro
Doomsday
The Persuader