Illinois State Route 13 is a highway in Eastern Jackson County. It is a four-lane highway from Murphysboro to the Jackson/Williamson County Line. IL St Rt 13 passes through the following towns in Jackson County. Vergennes Murphysboro
Carbondale IL St Rt 13 is multi-plexed in Jackson County. Illinois State Route 127, from the Jackson/Perry County Line to Murphysboro.