U.S. Rt. 41 runs straight through the center of this county. This is one place where the highway does not by-pass the major city. The by-pass is done by Interstate 164 to the east. U.S. Rt. 41 passes through the following town in Vanderburgh County. Evansville U.S. Rt. 41 is multi-plexed in Vanderburgh County. Indiana State Route 66, at Evansville. Indiana State Route 62, at Evansville. U.S. Rt. 41 intersects the following highways in Vanderburgh County. Indiana State Route 57, north of Evansville. Indiana State Route 66, at Evansville. Indiana State Route 62, at Evansville. Interstate 164, at Evansville.
BGS on WB I-164. A set of guide markers in Downtown Evansville. A BGS on EB Veterans Memorial Parkway. The C/D Lan on EB Veterans Memorial Parkway at I-164/U.S. Rt. 41. SB U.S. Rt. 41, south of I-164 near the Indiana/Kentucky State Line.
