U.S. Federal Route 18 runs east-west across Cerro Gordo County. This is a two-lane highway from the Cerro Gordo/Hancock County line to Interstate 35, near Clear Lake. From near Clear Lake it runs on a expressway to the Cerro Gordo/Floyd County Line. U.S. Rt 18 passes through the following towns in Cerro Gordo County. Ventura Clear Lake U.S. Rt. 18 is multi-plexed in Cerro Gordo County. BUSN Loop I-35, near Clear Lake. Interstate 35, near Clear Lake.
Iowa State Route 27, from near Clear Lake to the Cerro Gordo/Floyd County Line.