Iowa State Route 27 runs north-south along Interstate 35 from the Worth/Cerro Gordo County Line to near Clear Lake. South of Clear Lake, IA St Rt 27 runs east-west with U.S. Rt. 18 along a expressway from Interstate 35 to the Cerro Gordo/Floyd County Line. IA St Rt 27 is does not pass through any towns in Cerro Gordo County. IA St Rt 27 is multi-plexed in Cerro Gordo County. Interstate 35, from the Worth/Cerro Gordo County Line to near Clear Lake.
U.S. Rt. 18, from near Clear Lake to the Cerro Gordo/Floyd County Line.