U.S. Federal Route 65 is a north-south highway through Eastern Polk County. This runs along a four-lane highway with at-grade intersections from the Jasper/Polk County Line to near Altoona. At Altoona, it briefly runs with Interstate 80. Then on the eastside of Des Monies, this highway forms a outer expressway. U.S. Rt. 65 passes through the following towns in Polk County. Altoona Pleasant Hill Des Monies U.S. Rt. 65 is multi-plexed in Polk County. Interstate 80, near Altoona.
Iowa State Route 5, near the Polk/Warren County Line. U.S. Rt. 65 intersects the following highways in Polk County. Interstate 80, at Altoona. U.S. Rt. 6, at Altoona. Interstate 80, at Altoona. U.S. Rt. 6, at Altoona. Iowa State Route 163, near Pleasant Hill. Iowa State Route 5, near Carlisle.
A BGS on WB I-80/U.S. Rt. 6. A set of overhead signs on WB I-80/U.S. Rt. 6. A BGS on WB I-80/SB U.S. Rt. 65. WB I-80/SB U.S. Rt. 65 near Altoona.