U.S. Federal Route 6 runs east-west across Southern Polk County. This is one of the main surface streets through Metro-Des Monies. From Des Monies east it runs along Interstate 80 to the Polk/Jasper County Line. U.S. Rt. 6 passes through the following towns in Polk County. Altoona Des Monies Windsor Heights Clive Urbandale U.S. Rt. 6 is multi-plexed in Polk County. Interstate 80, from the Polk/Jasper County Line to Altoona. Iowa State Route 28, from Des Moines to Windsor Heights. U.S. Rt. 6 intersects the following highways in Polks County. Interstate 80, at Altoona. U.S. Rt. 65, at Altoona. U.S. Rt. 65, at Altoona. Interstate 235, at Des Monies. U.S. Rt. 69, at Des Monies. Iowa State Route 415, at Des Monies. Iowa State Route 28, at Des Monies. Iowa State Route 28, at Windsor Heights. Interstate 35, at Clive. Interstate 80, at Clive.