Iowa State Route 16 is the main east-west highway in Northern Lee County. This runs from a junction with U.S. Rt. 61, near Wever, to the Lee/Henry County Line, near Hillsboro. IA St Rt 16 passes through the following towns in Lee County. Denmark Houghton IA St Rt 16 is not multi-plexed in Lee County. IA St Rt 16 intersects the following highways in Lee County. U.S. Rt. 61, near Wever. U.S. Rt. 218, near Pilot Grove. Iowa State Route 27, near Pilot Grove.
