U.S. Federal Route 50 is the main east-west highway in Clay County. It runs mostly across the southern portion of the county. U.S. Rt. 50 passes through the following town in Clay County. Flora
U.S. Rt. 50 is multi-plexed in Clay County. U.S. Rt. 45, near Flora.
U.S. Rt. 50 intersects the following highways in Clay County. U.S. Rt. 45, near Flora.