What is "The Prophecy?"
 

"The Prophecy" was contained in a text revealed on one of the blank pages of a Rambaldi notebook, and intercepted by Sydney during an exchange between Mr. Sark and Lavro Kessar's men. In each of Rambaldi's notebooks, page 47 is known to hold particular significance. In this case, the invisible ink on the paper was revealed by the CIA, using liquid from the ampule retrieved during McKenas Cole's SD-6 takeover. The solution revealed an image of a woman's face, bearing striking resemblance to a young Sydney.

Excerpted, Rambaldi's "Prophecy" reads: "The woman here depicted will possess unseen marks. Signs that she will be the one to bring forth my works, bind them with fury; a burning anger. Unless prevented, at vulgar cost, this woman will render the greatest power unto utter desolation. This woman, without pretense, will have had her effect, never having seen the beauty of my sky, behind Mount Subasio. Perhaps a single glance would have quelled her fire."