Cast Tobey Maguire Spider-Man/Peter Parker Willem Dafoe Green Goblin/Norman Osborn Kirsten Dunst Mary Jane Watson James Franco Harry Osborn Cliff Robertson Uncle Ben Rosemary Harris Aunt May J.K. Simmons J. Jonah Jameson Joe Manganiello Flash Thompson Gerry Becker Maximilian Fargas Bill Nunn Joseph 'Robbie' Robertson Jack Betts Henry Balkan Stanley Anderson General Slocum Ron Perkins Dr. Mendell Stromm Michael Papajohn Carjacker K.K. Dodds Ellie Simkins Ted Raimi Hoffman Bruce Campbell Wrestling Ring Announcer Elizabeth Banks Betty Brant John Paxton Osborn's Houseman Tim Dezarn Philip Watson Taylor Gilbert Madeline Watson Randy Savage Bone Saw McGraw Larry Joshua Wrestling Promoter Timothy Patrick Quill Wrestling Arena Guard
Director: Sam Raimi Producers: Laura Ziskin and Ian Bryce Executive Producers: Avi Arad and Stan Lee Based on the Comic Book by: Stan Lee and Steve Ditko Screenplay: David Koepp Director of Photography: Don Burgess, ASC Production Designer: Neil Spisak Film Editors: Bob Murawski and Arthur Coburn, ACE Costume Designer: James Acheson Music By: Danny Elfman Casting: Francine Maisler and Lynn Kressel Visual Effects: John Dykstra, ASC Set Decorator: Karen O'Hara Art Directors: Tony Fanning and Stella Vaccaro
After being bitten by a radioactive spider, nerdy high school student Peter Parker finds his body chemistry altered so that he gains the powers of a spider and gains "spider-sense" that warns him of impending danger. Peter first uses his newfound powers to try to win some money in the wrestling arena, but after his uncle is murdered by a criminal Peter could have stopped but didn't, he swears to use his powers to fight evil.
Meanwhile, scientist and businessman Norman Osborne exposes himself to a new nerve gas he developed, which makes him psychotic and he becomes the Green Goblin. Parker is hired as a newspaper photographer for a tough newspaper editor, J. Jonah Jameson, in a battle against the Green Goblin, and trying to win the affections of Mary Jane Watson.