Intersections from west to east:

IL59 where Aurora meets Naperville

IL53 at Lisle

I-355 near Downers Grove*

IL83 near Hinsdale and Clarendon Hills

I-294 near Western Springs

US12/20/45 at La Grange

IL171 near Brookfield and Lyons

US34 ends in the east at IL43 near Lyons and Stickney.

It passes through these towns: Aurora, Naperville, Lisle, Downers Grove, Westmont, Hinsdale, Western Springs, Brookfield, and Lyons.

*- At the interchange of I-355 and US34, US34 also has access to/from the west on I-88.