The story begins with a young warrior prince who had to kill a
demon boar god in order to save his village from it's wrath. Because of this he was
cursed by the gigantic beast and had to leave his clan to never come back. His
only hope to survive the curse was to travel to the east of Japan and 'see with eyes
unclouded by hate' what had turned the god into a demon.
With this, the young prince Ashitaka starts his journey
towards a magical forest that, he heard, was guarded by a legendary spirit who
could cure him. Near it, he comes to Tatara Ba, a town ruled by Lady
Eboshi whose dream is to make Iron Town the stronger one, protect her outcast
villagers and kill the forest gods so that the humans, the invaders of that
place, can live in peace.
While in the town, he learns that Eboshi was the one who shoot
the boar god, turning him into a demon. When a girl raised by wolf gods appears
at Iron Town with the objective of killing the Lady and ends pen upped, Ashitaka
saves her and takes her back to her clan.
At the forest he tries to understand San, the Princess
Mononoke (princess of the spirits), and comes to know that she hates humans
because they are destroying all the nature and hunting the beast gods in order
to take the land for themselves. Later he comes back to Tatara Ba at the
same time that the boar's clan makes a final assault against the humans, Lady
Eboshi is coerced to chase down the forest guardian and Iron Town is attacked by
samurais.
When Ashitaka goes after the Lady and the strange monk that
wants the head of the guardian spirit for his emperor, they all come in front of
the god and Eboshi shoots his head off. After that, he slowly changes to a huge
monster and chases the holders of his head, while killing everything he touches.
Finally Ashitaka and San can stop the monk and return the head
to the headless spirit, who whoever dies when the first rays of sun hit him.
Nevertheless, the guardian restores the dead forest before he disappears.
At the end our young warriors part their ways with the promise
of coming back to visit each other. Now humans and nature were in peace.