Business U.S. Federal Route 218 runs into Charles City. The parent highway, U.S. Rt. 218, runs along the Avenue of Saints, which by-passes the town to the south. BUSN U.S. Rt. 218 passes through the following town in Floyd County. Charles City U.S. Rt. 218 is not multi-plexed in Floyd County. U.S. Rt. 218 intersects the following highways in Floyd County. U.S. Rt. 18, near Charles City. U.S. Rt. 218, near Charles City. Iowa State Route 27, near Charles City. U.S. Rt. 18, at Charles City. U.S. Rt. 218, near Charles City. Iowa State Route 27, near Charles City.
A BGS on EB U.S. Rt. 18; SB U.S. Rt. 218/IA St Rt 27. A guide marker on EB U.S. Rt. 18; SB U.S. Rt. 218/IA St Rt 27.