U.S. Federal Route 218 is a north-south highway in Eastern Floyd County. It runs from the Floyd/Mitchell County line to the Floyd/Chickasaw County Line. Near Floyd this highway enters the Avenue of Saints Corridor. Around Charles City it is on a interstate standard expressway. U.S. Rt. 218 passes through the following town in Floyd County. Floyd U.S. Rt. 218 is multi-plexed in Floyd County. U.S. Rt. 18, from near Floyd to near Charles City.
Branches of U.S. Rt. 218 in Floyd County. A junction marker on EB U.S. Rt. 18/SB IA St Rt 27. EB U.S. Rt. 18; SB U.S. Rt. 218/IA St Rt 27 north of Charles City. A set of guild markers on a ramp from EB U.S. Rt. 18; SB U.S. Rt. 218/IA St Rt 27. EB U.S. Rt. 18; SB U.S. Rt. 218/IA St Rt 27 near Charles City. SB U.S. Rt. 218/IA St Rt 27 south of Charles City.