U.S. Federal Route 151 runs east-west in Dubuque County. This is the northern most county that it passes through in the State of Iowa. U.S. Rt. 151 passes through the following towns in Dubuque County. Dubuque
U.S. Rt. 151 is multi-plexed in Dubuque County. U.S. Rt. 61, near Dubuque.