U.S. Federal Route 61 runs north-south along Eastern Dubuque County. This is the northern most county that it passes through in the State of Iowa. U.S. Rt. 61 passes through the following towns in Dubuque County. Zwingle Dubuque
U.S. Rt. 61 is multi-plexed in Dubuque County. U.S. Rt. 151, near Dubuque.