U.S. Federal Route 52 runs across eastern and northern Dubuque County. It is one of the main surface highways through Metro-Dubuque. U.S. Rt. 52 passes through the following towns in Dubuque County. St. Catherine Dubuque
Sageville Durango Rickardsville Luxemburg U.S. Rt. 52 is multi-plexed in Dubuque County. U.S. Rt. 61, at Dubuque. U.S. Rt. 151, at Dubuque.