Sabin

Sagat

SAMAS

Samus Aran

Sanjuro Makabe

Sara (BOF)

Sasuke (Goemon's Great Adventure)

Scorpion (MK)

Scott (Bogus)

Sektor (MK)

Selfie Tilmitt

Sephiroth

Shadow (Doomsday Warrior)

Shadow (FF3)

Shang Tsung

Shao Kahn

Sheena (Run Saber)

Sheeva (MK)

Sheila

Shin Kazama (U.N. Squadron)

Shiva (Final Fantasy)

Shivan Dragon

Sicdrenda

Sigma

Sindel (MK)

Sistoo (Mantis Warrior; One-on-One)

Sky (Skyblazer)

Skynet Robot (Fallout 2)

Slasher Hawk

Sledge

Slen

Slick Clyde

Smithy

Snake Man (Mega Man boss)

Solid Snake

Sonia (Sonic Blast Man 2)

Sonic Blast Man

Sonork (Dark Rift)

Spar (BOF 2)

Sprite (Secret of Mana)

Squall Leonheart

Ssapo (Bio F. R. E. A. K. S.)

Starsiege Tribesman: Heavy

Starsiege Tribesman: Light

Starsiege Tribesman: Medium

Stealth Tank (C&C)

Sten (BOF 2)

Storm (Chrono Trigger created)

Storm (X-Men)

Strago

Stryker (MK)

SubZero (MK)