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Earth-12131

A reality where a mysterious Pulse hit Earth, a phenomenon which affected technology worldwide, left strange energy signatures, and traces of a powerful material called Isotope-8, which had the ability to enhance its user's powers. S.H.I.E.L.D. created an Alliance of heroes lead by one of their newest agents, with the aim to collect Iso-8 before any supervillain could get their hands on it.

Heroes:
The Alliance

Known Teams:
The Avengers
The Fantastic Four
X-Men
Excalibur
The Guardians of the Galaxy
The Inhumans
The Runaways
S.H.I.E.L.D.

Villains:
Doctor Doom
The Red Skull
Living Pharaoh
Kang the Conqueror
Ultron
Mephisto
Blackheart
Thanos
Malekith
Kurse
Arcade
Apocalypse
Batroc
Carnage
Scream
The Serpent
Radioactive Man
Klaw
Morgan Le Fay
Ronan the Accuser
Nebula
Bastion
Sauron
Stegron the Dinosaur Man
High Evolutionary
The Absorbing Man
Dracula
Maximus the Mad
Surtur
Ymir
Hela
The Kingpin of Crime
Flag-Smasher
Ultimate Ultron
Karn
Yellowjacket
Mandarin
Morlun
Umar
Purple Man
The Shocker
The Beetle
The Leader
Zzzax
Count Nefaria
Crossfire
Graviton
The Rhino
Mister Hyde
Tiger Shark
Living Laser
The Ghost
Magus

Villainous Groups:
The Syndicate
The Circle of Eight
The Worthy
The Brotherhood of Evil Mutants
HYDRA
A.I.M.
The Hand
The Maggia
The Hellfire Club
R.A.I.D.
The Sinister Six
The Wrecking Crew
The U-Foes
The Sentinels
The Horsemen of Apocaylpse
The Black Order
The Dark Avengers
The Symbiotes
The Jotun
The Dark Elves
The White Gorrilas
U.L.T.I.M.A.T.U.M.